Diagnosis and management of group B streptococcus in pregnancy

Homa K Ahmadzia; R Phillips Heine

doi:10.1016/j.ogc.2014.08.009

Diagnosis and management of group B streptococcus in pregnancy

Obstet Gynecol Clin North Am. 2014 Dec;41(4):629-47. doi: 10.1016/j.ogc.2014.08.009. Epub 2014 Nov 20.

Authors

Homa K Ahmadzia¹, R Phillips Heine²

Affiliations

¹ Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Duke University Medical Center, DUMC 3967, Durham, NC 27710, USA.
² Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Duke University Medical Center, DUMC 3967, Durham, NC 27710, USA. Electronic address: phillip.heine@dm.duke.edu.

PMID: 25454995
DOI: 10.1016/j.ogc.2014.08.009

Abstract

Group B streptococcus (GBS) can cause significant maternal and neonatal morbidity. Over the past 30 years, reductions in early-onset GBS neonatal sepsis in the United States have been attributable to the guidelines from the Centers for Disease Control and Prevention for antepartum screening and treating this organism during labor. This article highlights the clinical implications, screening, diagnosis, prophylactic interventions, and future therapies for mothers with GBS during the peripartum period.

Keywords: Diagnosis; Group B streptococcus; Intrapartum prophylaxis; Neonate; Pregnancy; Screening.

Publication types

Review

MeSH terms

Adult
Anti-Bacterial Agents / administration & dosage*
Antibiotic Prophylaxis / methods*
Drug Administration Schedule
Female
Humans
Infant, Newborn
Infant, Newborn, Diseases / epidemiology
Infant, Newborn, Diseases / microbiology*
Infectious Disease Transmission, Vertical / prevention & control*
Practice Guidelines as Topic
Pregnancy
Pregnancy Complications, Infectious / epidemiology
Pregnancy Complications, Infectious / microbiology*
Pregnancy Complications, Infectious / prevention & control
Premature Birth
Prenatal Diagnosis
Risk Factors
Sepsis / epidemiology
Sepsis / microbiology*
Sepsis / prevention & control
Streptococcal Infections / epidemiology
Streptococcal Infections / microbiology*
Streptococcal Infections / prevention & control
Streptococcal Vaccines
United States / epidemiology

Substances

Anti-Bacterial Agents
Streptococcal Vaccines